Polytherapy with two or more antihypertensive drugs to lower blood pressure in elderly Ontarians. Room for improvement
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چکیده
منابع مشابه
Aspirin and blood pressure: Effects when used alone or in combination with antihypertensive drugs.
Arterial hypertension is a major risk factor for cardiovascular and renal events. Lowering blood pressure is thus an important strategy for reducing morbidity and mortality. Since low-dose aspirin is a cornerstone in the prevention of adverse cardiovascular outcomes, combined treatment with aspirin and antihypertensive drugs is very common. However, the impact of aspirin therapy on blood pressu...
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Approximately 30-40% of patients do not achieve seizure control with a single antiepileptic drug (AED). With the advent of multiple AEDs in the past 15 years, rational polytherapy, the goal of finding combinations of AEDs that have favorable characteristics, has become of greater importance. We review the theoretical considerations based on AED mechanism of action, animal models, human studies ...
متن کاملPrimary Aldosteronism With Type 2 Diabetes Mellitus Requires More Antihypertensive Drugs for Blood Pressure Control: A Retrospective Observational Study
Background Diabetes mellitus (DM) and primary aldosteronism (PA) have been reported to induce drug-resistant hypertension and atherosclerosis. It is likely that blood pressure (BP) control becomes far more difficult in PA patients with DM. However, precise clinical characteristics of PA with type 2 DM especially in the aspect of BP control are not clear. Methods The study included 18 patients...
متن کاملArterial pressure responses to discontinuing antihypertensive drugs.
rose promptly and treatment was restarted within a month. Among essential hypertensive patients, those who remained off treatment for 2 to 6 months had significantly lower pretreatment pressure than those whose hypertension returned in less than 2 months. The two whose diastolic hypertension seemed "cured" had no distinguishing features. These results suggest that most hypertensive patients req...
متن کاملReturn of elevated blood pressure after withdrawal of antihypertensive drugs.
The rate at which arterial pressure rises after discontinuing active treatment was investigated in a group of 86 hypertensive patients who received treatment with hydrochlorothiazide, reserpine and hydralazine for two years or longer and whose diastolic pressures averaged below 96 mm Hg for the last year of treatment. Sixty patients were assigned double-blind to placebos and 26 were continued o...
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ژورنال
عنوان ژورنال: Canadian Journal of Cardiology
سال: 2007
ISSN: 0828-282X
DOI: 10.1016/s0828-282x(07)70827-9